Aβ (1-42) is soluble in hexafluoroisopropanol (HFIP), DMSO, 0.1% aqueous ammonia, 50 mM TRIS ∙ HCl, or 1 mM NaOH. Reconstitution in HFIP or DMSO requires time whereas ammonia swiftly dissolves the peptide. The volatile solvent HFIP is usually vaporized leaving a deposit of monomeric, soluble Aβ (1-42), which can...
